Our research focuses on the diagnosis, pathogenesis, and treatment of human adrenal disorders and tumors. These research initiatives are closely tied to our clinical efforts in the BWH Center for Adrenal Disorders.
Our research approach involves patient-oriented physiology studies and deep phenotyping protocols to gain insights into adrenal hormone biology. In parallel, we conduct prospective cohort and intervention studies to understand the health implications of these findings.
Our major efforts have focused on better characterizing the spectrum of primary aldosteronism, the distribution of clinically relevant adrenal hormone excess that imparts adverse health effects, the pathogenesis and treatment of adrenal tumors, and improving quality of life for patients with adrenal insufficiency.
Recent Lab Updates
2019 Update: Our case-based overview on the management of Incidentally Discovered Adrenal Masses for AACE.
2018 Update: Our comprehensive and contemporary review on Primary Aldosteronism was published in Endocrine Reviews.
2018 Update: Our cohort studies evaluating the efficacy of currently recommended treatments for primary aldosteronism were published in The Lancet Diabetes & Endocrinology, JAMA Cardiology, and Hypertension.
2018 Update: Our international collaborative published new findings implicating EPAS1 mutations in paragangliomas of patients with cyanotic congenital heart disease in the New England Journal of Medicine
2017 Update: A review article on Aging and Aldosterone Production published in collaboration with the Rainey Lab at the University of Michigan.
2017 Update: The lab's new research on Subclinical Primary Aldosteronism published in Annals of Internal Medicine.
2017 Update: The Vaidya Lab publishes new studies on primary aldosteronism pathophysiology and treatment in Annals of Internal Medicine and The Lancet Diabetes & Endocrinology.
2016 Update: Dr. Vaidya discusses the lab's new research on "non-functional" adrenal tumors published in Annals of Internal Medicine.