Our research group is part of the Center for Adrenal Disorders at Brigham and Women's Hospital and the Division of Endocrinology, Diabetes, and Hypertension.

Our research focuses on human adrenal disorders and tumors. We conduct human physiology studies, deep phenotyping protocols, and prospective studies to gain insights into adrenal hormone biology. Our major efforts have focused on characterizing the syndrome of primary aldosteronism, the distribution of clinically relevant adrenal hormone excess that imparts adverse health effects, the pathogenesis and treatment of adrenal tumors, and improving quality of life for patients with adrenal insufficiency.

Recent Lab Updates

2020 Update: We characterized the unrecognized prevalence of primary aldosteronism. This multi-site study in Annals of Internal Medicine redefines primary aldosteronism as a common syndrome that can manifest across a broad continuum of severity. Editorial by Prof. John Funder.

2019 Update: Our case-based overview on the management of Incidentally Discovered Adrenal Masses for AACE.

2018 Update: Our comprehensive and contemporary review on the Expanding Spectrum of Primary Aldosteronism was published in Endocrine Reviews.

2018 Update: Our cohort studies evaluating the efficacy of currently recommended treatments for primary aldosteronism were published in The Lancet Diabetes & Endocrinology, JAMA Cardiology, and Hypertension.

2018 Update: Our international collaborative published new findings implicating EPAS1 mutations in paragangliomas of patients with cyanotic congenital heart disease in the New England Journal of Medicine

2017 Update: A review article on Aging and Aldosterone Production published in collaboration with the Rainey Lab at the University of Michigan.

2017 Update: The lab's new research on Subclinical Primary Aldosteronism published in Annals of Internal Medicine.

2017 Update: The Vaidya Lab publishes new studies on primary aldosteronism pathophysiology and treatment in Annals of Internal Medicine and The Lancet Diabetes & Endocrinology.

2016 Update: Dr. Vaidya discusses the lab's  new research on "non-functional" adrenal tumors published in Annals of Internal Medicine.